Hydroxypropyl methyl cellulose HPMC o se non-ionic cellulose fefiloi eter i se ituaiga ma ionic methyl carboxymethyl cellulose fefiloi eter, e le tali atu i metals mamafa. O le tasi o le okesene radicals ona o le hydroxypropyl methyl cellulose content ma le eseese o vaega o le hydroxypropyl content ma le viscosity, na avea ma ituaiga eseese i luga o le faatinoga, mo se faʻataʻitaʻiga, maualuga methoxyl anotusi ma mea maualalo o ituaiga hydroxypropyl, o lona faatinoga e latalata i le methyl cellulose ma le maualalo methoxyl anotusi ma mea maualuga o ituaiga hydroxypropyl, ma o lona faatinoga e latalata i le hydroxypropyl methyl cellulose ua gaosia. Ae i ituaiga taʻitasi, e ui lava o loʻo i ai se vaega itiiti o le hydroxypropyl poʻo se vaega itiiti o le methoxy, o le solubility i solvents organic poʻo le vevela o le flocculation i le vai vaifofo, o loʻo i ai se eseesega tele.
1, hydroxypropyl methyl cellulose solubility
Hydroxypropyl methyl cellulose i le vai solubility o le hydroxypropyl methyl cellulose o le mea moni o se ituaiga o propylene oxide (methyl oxypropyl mama) suia methyl cellulose, o lea e tutusa lava ma methyl cellulose vai malulu soluble ma vai vevela uiga insoluble. Ae ui i lea, o le vevela o le gelation o le hydroxy propyl ua suia e sili atu le maualuga nai lo le methyl cellulose i le vai vevela. Mo se faʻataʻitaʻiga, o le viscosity o le hydroxypropyl methylcellulose aqueous solution ma le 2% methoxy content DS=0.73 ma le hydroxypropyl content MS=0.46 o le 500 mpa i le 20 ℃. Ole vevela ole gel ole oloa ole S e latalata ile 100℃, ae ole methyl cellulose ole vevela tutusa e na'o le 55℃. A o lona solubility i le vai, ua matua faaleleia foi, mo se faataitaiga, ina ua uma le nutimomoia o le hydroxypropyl methylcellulose (saito foliga 0.2 ~ 0.5mm i le 20 ℃ 4% aqueous viscosity o 2pA? S oloa e mafai ona faigofie solo i le vai e aunoa ma le malulu i le vevela o le potu. .
(2) Hydroxypropyl methyl cellulose i solubility solubility o le hydroxypropyl methyl cellulose i solubility solubility, e sili atu foi nai lo methyl cellulose, methyl cellulose manaomia i le methoxy suitulaga tikeri o le 2.1 po o le sili atu oloa, ma e aofia ai hydroxypropyl MS = 1.5 ~ 1.8 ma methoxy. DS = 0.2 ~ 1.0, High viscosity hydroxypropyl methyl cellulose fa'atasi ai ma le tikeri fa'asolo atoa i luga a'e o le 1.8 e mafai ona solu ile methanol anhydrous ma vaifofo ethanol, ma e iai le vevela ma le vai solubility. E mafai foi ona solu i totonu o le chlorinated hydrocarbons e pei o le dichloromethane ma trichloromethane, ma solvents organic pei ole acetone, isopropyl alcohol, ma le diacetone alcohol. O lona solubility i soluble organic e sili atu nai lo le solubility i le vai.
2, hydroxypropyl methyl cellulose viscosity o mea e aʻafia ai
Hydroxypropyl methylcellulose viscosity mea hydroxypropyl methylcellulose tulaga viscosity determination, ma isi cellulose ether e tutusa, o loo i le 20 ℃ ma le 2% vai vai e pei o le filifiliga masani. O le viscosity o le oloa lava e tasi, faatasi ai ma le faateleina o le faʻatonuga ma le faʻateleina, o le faʻaogaina tutusa o oloa mamafa mole mole eseese, mamafa mole o le oloa e maualuga le viscosity. O lona sootaga ma le vevela e tutusa ma le methyl cellulose. A oʻo i luga le vevela, e amata ona paʻu le viscosity, ae a oʻo i se vevela, faʻafuaseʻi ona oso aʻe le viscosity ma tupu ai le gelation. O le vevela o le gelation o oloa e maualalo le viscosity e maualuga atu nai lo oloa e maualuga le viscosity. Ole maualuga ole mata ole gel, e faaopoopo atu ile maualuga ma le maualalo ole viscosity ole ether, ae faʻapea foʻi ma le eter methoxy ma le hydroxypropyl group composition ratio ma le tikeri atoa o le suitulaga e fesoʻotaʻi. E tatau ona maitauina o le hydroxypropyl methylcellulose o le pseudoplastic foi; o lona fofo e mautu pe a teuina i le vevela o le potu ma e le faʻaalia ai soʻo se faʻaleagaina o le viscosity vagana ai le avanoa e faʻaleagaina ai le enzymatic.
3, hydroxypropyl methyl cellulose acid ma alkaline tetee
Hydroxypropyl methylcellulose acid alkali hydroxypropyl methylcellulose acid ma alkali, e masani lava e mautu, i le ph PH2 ~ 12 laina e le afaina, e mafai ona tetee atu i se aofaiga faapitoa o le malamalama, e pei o le formic acid, acetic acid, citric acid, succinic acid, phosphoric. acid, boric acid, ma isi. Ae o le acid concentrated ei ai le aafiaga o le faaitiitia o le viscosity. Alkali e pei o le soda, caustic potassium ma le lime vai e leai se aoga i ai, ae o le aʻafiaga o le faʻateleina o le viscosity o le fofo o le a faʻaitiitia lemu i le lumanaʻi.
4, hydroxypropyl methyl cellulose e mafai ona faʻafefiloi
Hydroxypropyl methyl cellulose solution e mafai ona faʻafefiloi ma vai-soluble polymer compounds, ma avea ma se vaifofo manino tutusa ma maualuga viscosity. O nei vaega mole mole maualuga o le polyethylene glycol, polyvinyl acetate, polysilicone, polymethyl vinyl siloxane ma le hydroxyethyl cellulose ma le methyl cellulose, ma isi mea faʻapipiʻi masani polymer e pei o gum Arabic, gocust bean gum, laau talatala ma isi mea e iai foi se paluga lelei ma lona. fofo. Hydroxypropyl methyl cellulose e mafai foi ona faʻafefiloi ma le stearic acid poʻo le palmitic acid mannitol ester poʻo le sorbitol ester, ae faʻapea foʻi ma le glycerol, sorbitol ma le mannitol, e mafai ona faʻaaogaina nei mea e pei o le hydroxypropyl methyl cellulose plasticizer.
5, hydroxypropyl methyl cellulose vai soluble
Hydroxypropyl methyl cellulose insoluble vai-soluble cellulose ether, e mafai ona i luga o le satauro-so'ota'i ma aldehydes, ma faia nei vai soluble eter precipitated i le vaifofo, avea insoluble i le vai. Ma faia hydroxypropyl methylcellulose insoluble aldehyde, formaldehyde, glyoxal, succinaldehyde, dialdehyde, ma isi, o le faaaogaina o formaldehyde e tatau ona gauai faapitoa atu i le tau o le PH o le vaifofo, lea glyoxal tali vave, o lea i le gaosiga o alamanuia masani ona faaaoga glyoxal e pei o se koluse. -so'ota'i sui. O le fua o lenei ituaiga o sui sooupu crosslinking i le vaifofo o le 0.2% ~ 10% o le ether tele, o le sili e 7% ~ 10%, e pei o le faaaogaina o le glyoxal ma le 3.3% ~ 6% e sili ona talafeagai. Ole vevela ole togafitiga masani ole 0~30℃, ole taimi ole 1~120min. E mana'omia ona faia le fa'agasologa o feso'ota'iga i lalo ole tulaga fa'ama'i. E masani lava, e faʻapipiʻi i le vaifofo le faʻaogaina o le PH o le vaifofo e uiga i le 2 ~ 6, e sili i le va o le 4 ~ 6, ona faʻaopoopoina lea o aldehydes mo le faʻafesoʻotaʻi tali. O vailaʻau o loʻo faʻaaogaina o le hydrochloric acid, sulfuric acid, phosphoric acid, formic acid, acetic acid, hydroxy acetic acid, succinic acid poʻo le citric acid, e aofia ai le formic acid poʻo le acetic acid e sili ona lelei, ae o le formic acid e sili ona lelei. O acids ma aldehydes e mafai foi ona faaopoopo i le taimi e tasi ina ia mafai ai ona faʻafesoʻotaʻi le vaifofo i le PH e manaʻomia. O lenei tali e masani ona faʻaaogaina i le faagasologa mulimuli o le cellulose ether preparation process, ina ia le faʻamavaeina le cellulose ether, faigofie ona faʻaoga 20 ~ 25 ℃ vai e fufulu ma faʻamamā. A faʻaaogaina le oloa, e mafai ona faʻaopopo mea alkaline i le fofo o le oloa e faʻafetaui ai le PH o le fofo e avea ma alkaline, ma o le oloa e vave faʻamavae i le fofo. E mafai fo'i ona fa'aoga lenei metotia pe a fa'aogaina le cellulose ether solution e fai ai se ata ona togafitia lea o le ata e fai ai se ata e le mafai ona fa'afefeteina.
6, hydroxypropyl methyl cellulose anti-enzyme
Hydroxypropyl methyl cellulose enzyme tetee o cellulose derivatives i le teori, e pei o vaega taitasi anhydroglucose e pei o loo i ai se tuufaatasiga mausali o sui vaega, tafiesea o microorganisms e itiiti le aafia i siama, ae o le mea moni o le oloa maeʻa e sui ai le tau sili atu nai lo le 1, fa'apea fo'i ma le fa'aleagaina o le enzyme, o le fa'amatalaga lea o vaega ta'itasi i le cellulose filifili suitulaga tikeri e le tutusa, Microorganisms e mafai ona tafi latalata unsubstituted. vaega o le kulukose fa'amama vai e fai ai suka, e mafai ona mitiia e meaola ninii e fai ma mea'ai. O le mea lea, afai e faʻatuputeleina le maualuga o le suitulaga o le cellulose, o le a faʻaleleia le tetee o le cellulose ether i le faʻaleagaina o le enzymatic. Ua lipotia mai i lalo o tulaga pulea, o le viscosity totoe o le hydroxypropyl methyl cellulose (DS=1.9), methyl cellulose (DS=1.83), methyl cellulose (DS=1.66), ma le hydroxyethyl cellulose (1.7%) o le 13.2%, 7.3% , 3.8%, ma le 1.7%, i le faasologa. Hydroxypropyl methyl cellulose o loʻo i ai le malosi o le anti-enzyme. O lea la hydroxypropyl methylcellulose anti-enzyme sili ona lelei, faʻatasi ma lona faʻasalalau lelei, mafiafia ma ata faʻavae, faʻaaogaina i le emulsion coatings, ma isi, e masani lava e le manaʻomia le faʻaopoopoina o mea faʻasao. Ae ui i lea, ina ia puipuia le teuina mo se taimi umi o le fofo poʻo le faʻaleagaina mai le lalolagi i fafo, e mafai ona faʻapipiʻi mea faʻasao, o lana filifiliga e mafai ona fuafua e tusa ai ma manaoga mulimuli o le fofo. Phenylmercuric acetate ma manganese fluosilicate o ni puipuiga lelei, ae e oona ma e tatau ona faʻagaioia ma le faaeteete. E masani lava, 1 ~ 5mg phenylmercuric acetate e mafai ona faʻaopopo i lita taʻitasi o fofo.
7, hydroxypropyl methyl cellulose membrane faatinoga
Hydroxypropyl methyl cellulose ata tifaga faatinoga o le hydroxypropyl methyl cellulose o loʻo i ai ata sili ona lelei, o lona vaifofo vai poʻo le vaifofo soʻomea, faʻapipiʻiina i luga o le ipu tioata, pe a uma ona faʻamago e avea ma ata e leai se lanu, manino ma faigata. E lelei le susū e tete'e ma tumau mausali i le vevela maualuga. E pei o le faʻaopoopoga o le hygroscopic plasticizer, e mafai ona faʻaleleia lona faʻalauteleina ma le fetuutuunai, e faʻaleleia atili ai le flexure, glycerol ma sorbitol ma isi plasticizer e sili ona talafeagai. Ole faʻatonuga lautele ole fofo ole 2% ~ 3%, o le vailaʻau plasticizer o le 10% ~ 20% o le cellulose ether. Afai o mea o loʻo i totonu o le plasticizer e manaʻomia, o le faʻaitiitia o le faʻamaʻi o le colloid e mafai ona tupu i le maualuga o le susu. O le malosi faʻamalosi o le faʻapipiʻi faʻapipiʻi ata e sili atu le tele nai lo le mea e le faʻaopoopoina, ma faʻateleina i le faʻaopoopoga o le aofaʻi o le faʻaopoopoga, aua o le hygroscopicity o le ata e faʻateleina foi i le faʻaopoopoga o le aofaʻi o le plasticizer.
Taimi meli: Sep-08-2022