O le Hydroxypropyl methylcellulose (HPMC) o se polymer sili ona lelei ma faʻaaogaina i pisinisi eseese, e lauiloa mo ona uiga faʻapitoa ma faʻaoga.O lenei tuufaatasiga o se mea e maua mai i le cellulose, o se polymer masani e maua i totonu o puipui o laau.Ina ia malamalama i le tuufaatasiga o le hydroxypropylmethylcellulose, e tatau ona suʻesuʻe i totonu o le fausaga ma le tuʻufaʻatasia o lenei mea e maua mai i le cellulose.
Le fausaga o le cellulose:
O le cellulose o se ga'o ga'o lavelave e aofia ai se filifili laina o iunite β-D-glucose e feso'ota'i i fusi β-1,4-glycosidic.O nei kulukose filifili o lo'o u'u fa'atasi e fa'amauga hydrogen e fau ai se fausaga fa'a laina malo.O le Cellulose o le vaega autu o le fausaga o puipui o laau toto, e maua ai le malosi ma le maaa i sela laau.
O mea na maua mai le Hydroxypropyl Methylcellulose:
O le Hydroxypropyl methylcellulose o loʻo faʻapipiʻiina e ala i le faʻaogaina o le cellulose ma faʻafeiloaʻi vaega hydroxypropyl ma methyl i le filifili autu o le cellulose.O gaosiga e masani ona aofia ai laasaga nei:
Tali etherification:
Methylation: Totogiina o le cellulose i se vaifofo alkaline ma le methyl chloride e faʻafeiloaʻi ai vaega methyl (-CH3) i totonu o vaega hydroxyl (-OH) o le cellulose.
Hydroxypropylation: Methylated cellulose toe tali atu i le propylene oxide e faʻafeiloaʻi ai vaega hydroxypropyl (-CH2CHOHCH3) i totonu o le fausaga o le cellulose.O lenei faiga e faʻaleleia ai le solubility i le vai ma suia ai mea faitino o le cellulose.
fa'amamāina:
Ona fa'amamāina lea o le cellulose ua suia e aveese ai so'o se mea e le'i fa'aogaina, mea e maua mai po'o mea leaga.
Fa'amago ma olo:
Ole hydroxypropyl methylcellulose fa'amama e fa'amago ma fa'apala i se pauta lelei ua saunia mo le fa'aoga i le tele o talosaga.
Vaega o le Hydroxypropyl Methylcellulose:
O le tuufaatasiga o le hydroxypropyl methylcellulose o loʻo faʻaalia i le tikeri o le suitulaga, lea e faʻatatau i le tikeri o le hydroxypropyl ma le methyl vaega e sui ai vaega hydroxyl i le filifili cellulose.Eseese togi o le HPMC e eseese tikeri o le suitulaga, e aafia ai lo latou solubility, viscosity ma isi meatotino.
O le fua fa'atatau o le hydroxypropyl methylcellulose e mafai ona fa'amatalaina (C6H7O2(OH)3-mn(OCH3)m(OCH2CH(OH)CH3)n)_x, lea o le m ma le n o lo'o fa'atusalia ai le tikeri o le suitulaga.
m: tikeri o le methylation (vaega methyl i le kulukose iunite)
n: tikeri ole hydroxypropylation (vaega hydroxypropyl ile kulukose iunite)
x: numera o iunite kulukose i le filifili cellulose
Vaega ma Fa'aoga:
Solubility: HPMC e solu vai, ma o le tikeri o le suitulaga e aafia ai ona uiga solubility.E fausia ai se vaifofo manino ma viscous i totonu o le vai, e talafeagai ai mo le tele o fua.
Viscosity: O le viscosity o le HPMC solution e fa'alagolago i mea e pei o le mamafa mole mole ma le tikeri o le suia.O lenei meatotino e taua tele mo faʻaoga e pei o vailaʻau e manaʻomia ai faʻatonuga faʻasaʻo.
Fuaina o Ata: E mafai e le HPMC ona fai ni ata manifinifi pe a mago le vaifofo, ma fa'aaogaina i fa'alavalava i fale talavai, mea'ai ma isi pisinisi.
Stabilizers and Thickeners: I totonu o pisinisi taumafa, HPMC o loʻo faʻaaogaina e avea o se mafiafia ma faʻamautu i oloa eseese, e aofia ai sosi, suamalie, ma mea tao tao.
Talosaga Fa'afoma'i: O le HPMC o lo'o fa'aaogaina lautele i vaila'au fa'afoma'i, e aofia ai papama'a, capsules, ma vaifofo ophthalmic, ona o lona fa'asa'olotoina o meatotino ma le biocompatibility.
Fausia ma faʻaofuofu: E faʻaaogaina le HPMC i mea faufale e pei o sima, faʻapipiʻi taʻavale ma faʻamalama.E faʻaaogaina foi e avea o se mafiafia ma faʻamautu i vali ma faʻapipiʻi faʻapipiʻi.
Oloa Tausiga a le Tagata Lava Ia: I totonu o fale teuteu ma le tausiga o le tagata lava ia, o lo'o maua le HPMC i oloa e pei o kulimi, lotion ma shampoos, lea e maua ai le tino ma le mautu.
Hydroxypropyl methylcellulose e maua i le methylation ma le hydroxypropylation o le cellulose.O se polymer e tele-purpose ma le tele o faʻaoga.O ona uiga fa'apitoa e fa'atauaina ai i alamanuia e pei o vaila'au, mea'ai, faufale ma tausiga a le tagata lava ia.O le fa'atonutonuina o suiga ole cellulose e mafai ona fa'afetaui lelei meatotino a le HPMC, ma avea ai ma vaega taua o le tele o oloa tatou te feagai i o tatou olaga i aso faisoo.
Taimi meli: Ian-10-2024